Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0316988
PubChem CID
Molecular Formula
C14H18N2O2
Molecular Weight
246.31 g/mol
Synonyms/Alias
[CHEMBL563848; SCHEMBL7559030; XWTAQEXSIBGWRM-UHFFFAOYSA-N; BDBM50296730; phenyl 1;4-diazabicyclo[3.2.2]nonane-4-carboxylate; 1;4-Diaza-bicyclo[3.2.2]nonane-4-carboxylic acid phenyl ester]
InChI Key
XWTAQEXSIBGWRM-UHFFFAOYSA-N
InChI
InChI=1S/C14H18N2O2/c17-14(18-13-4-2-1-3-5-13)16-11-10-15-8-6-12(16)7-9-15/h1-5,12H,6-11H2
IUPAC Name
phenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate
CAS Number
298198-52-4

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

36 38 0 0 0 0 0 0 0 0999 V2000
-3.0059 -1.5045 0.6060 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.7792 -0.9259 -0.6025 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.1646 0.307...

Experimental Data

Activity Data

Target Ion Channel
5-hydroxytryptamine receptor 3A
Uniprot Accession Number
Function
Antagonist
Species
Mus musculus (Mouse)
IC50
N/A (Not available)
EC50
N/A (Not available)
Ki
Ki: 3993 nM
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
Not specified
Temperature
37 °C
Test Method
Binding assay ([3H] LY-278584)
Test Species
HEK293 cell (Homo sapiens embryonic kidney 293 cell)

Binding Information

Binding Site
extracellular domain
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
18
Rotatable Bonds
1
logP
1.9654
Complexity
68.634
TPSA (Ų)
32.78
H-Bond Donors
0
H-Bond Acceptors
3
Ring Count
4
New Search